Model Perspective

Feb 23, 2026 · Fundamentals

Can You Really Train Your Alcohol Tolerance? The Science Behind Drinking Capacity

This article explains how alcohol is metabolized, why many East Asians experience flushing due to the ALDH2*2 genetic variant, how a simple pharmacokinetic model predicts acetaldehyde buildup, and why perceived drinking tolerance is driven by neural adaptation rather than metabolic improvement.