Data Party THU

Oct 24, 2026 · Artificial Intelligence

Do We Really Know What Biomedical Foundation Models Have Learned? Benchmarking Challenges Revealed

A Nature Methods paper argues current leaderboard-style benchmarks fail to capture true generalization of biomedical foundation models, advocating perturbation-based tests, ablation studies, and a community-driven ecosystem (BEACON) to evaluate mechanistic understanding beyond single-task scores.