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CASP16

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HyperAI Super Neural
HyperAI Super Neural
Jul 16, 2026 · Artificial Intelligence

RNAbpFlow Rivals AlphaFold 3 in RNA Structure Prediction Without Evolutionary Data

The Virginia Tech team introduced RNAbpFlow, a SE(3)-equivariant flow‑matching model that predicts full‑atom RNA 3D structures using only sequence and base‑pair information, achieving higher TM‑score and lDDT than AlphaFold 3 on CASP16 targets and outperforming existing methods across multiple benchmarks.

AlphaFold 3CASP16RNA structure prediction
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RNAbpFlow Rivals AlphaFold 3 in RNA Structure Prediction Without Evolutionary Data