Network Intelligence Research Center (NIRC)

Oct 17, 2025 · Artificial Intelligence

LucaOne: Unified Nucleic Acid & Protein Language Model Surpasses Other Models

Researchers present LucaOne, a Transformer‑based foundation model that unifies DNA/RNA and protein sequences using a 39‑token vocabulary, rotary positional encoding, and molecule‑type embeddings, and demonstrate through extensive multi‑task benchmarks that it outperforms domain‑specific models across seven biological tasks.