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prefrontal cortex

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Data Party THU
Data Party THU
Oct 9, 2026 · Artificial Intelligence

Nature Cover: 6.3M-Cell Atlas Reveals Largest Human Brain Gene Activity Map Across Aging and Disease

The PsychAD consortium analyzed 6.3 million single-nucleus transcriptomes from 1,494 donors spanning infancy to 108 years, creating the largest prefrontal cortex atlas to date and revealing shared and disease-specific molecular changes across eight brain disorders using AI-driven graph neural networks.

Nature publicationPsychAD consortiumbrain aging
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Nature Cover: 6.3M-Cell Atlas Reveals Largest Human Brain Gene Activity Map Across Aging and Disease