Machine Heart
Nov 13, 2026 · Artificial Intelligence
MolRSI: Self-Improving AI Agent Doubles Wet-Lab Hit Rates in Molecular Discovery
MolRSI, a recursive self-improving AI agent, optimizes molecular discovery workflows through dual-loop experience transfer, achieving 15.9% experimental hit rate in antimicrobial screening (82% improvement over human experts) and 8 specific pMHC binders versus zero for Claude Science, demonstrating that AI-driven workflow optimization translates to wet-lab success.
AI AgentMolRSIRecursive Self-Improvement
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