MIT’s APOLLO Framework Breaks Limits, Separating Shared and Modality‑Specific Cell Signals
MIT and ETH Zurich introduce APOLLO, a deep‑learning autoencoder that learns a partially overlapping latent space to explicitly disentangle shared and modality‑specific information in multimodal single‑cell datasets, demonstrating superior cell‑type classification, cross‑modal prediction, and protein localization insights across sequencing and imaging data.
