Machine Heart
Aug 30, 2026 · Artificial Intelligence
How Large Discovery Models Enable AI to Design the Next Experiment
The Large Discovery Model (LDM) combines a generative foundation model with a Gaussian‑process reward model to create fast and slow learning loops that iteratively propose, evaluate, and refine experimental designs across neural‑network training, antibody engineering, and small‑molecule optimization, achieving significant performance gains over pure LLM or Bayesian‑optimization baselines.
Bayesian optimizationLarge Discovery Modelsantibody design
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